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Tronc Commun - UE-M-ADPH-PhMat : UE 14 Pharmaceutical material engineering


The pharmaceutical industry is increasingly looking for engineers and pharmacists with advanced training in pharmaceutical engineering. The aim of this course is to fill a need for engineers and pharmacist students who wish to develop skills to work in pharmaceutical product design and manufacturing.

With core strengths in fundamental powder and particle engineering, this course will give the opportunity to gain knowledge in areas of concern to pharmaceutical industry such as pharmaceutical materials engineering.

Particle design by encapsulation will also be addressed as part of this course.

Objectifs pédagogiques

Upon completion of this program students will be able to:

-Explain the role of pharmaceutical materials engineering in drug development;

-Recognize the role of excipients in creating and stabilizing multi-component solid in the solid state (using an example of solid dispersions);

-Evaluate process technology and processing conditions when formulating pharmaceutical solid forms by encapsulation;

-Become familiar with the main principles in the field of pharmaceutical materials engineering and particle design by encapsulation.

77.5 heures en présentiel
réparties en:
  • Evaluation des connaissances et capacités : DS, QCM, présentation orale : 3.5
  • Cours Magistraux : 74

21 heures de travail personnel estimé pour l’étudiant.

effectifs minimal / maximal:


Diplôme(s) concerné(s)

Format des notes

Numérique sur 20

Littérale/grade européen

Pour les élèves du diplômeAdvanced Pharmaceutical Engineering

L'UE est acquise si Note finale >= 10 et aucune Note finaledes Modules <10
  • Crédits ECTS acquis : 6 ECTS

La note obtenue rentre dans le calcul de votre GPA.

Programme détaillé

M141. Introduction to the pharmaceutical forms

  • Pharmacokinetics & biopharmaceutics; preformulation; introduction to the pharmaceutical dosage forms
  • Solubility & dissolution


M142. Pharmaceutical materials engineering (solid forms)

  • Solid form screening
  • Crystal engineering
  • Crystal particle size reduction (micronisation-milling)
  • Crystalline drug production - nanotechnologies
  • A disordered pharmaceutical material: the amorphous state
  • Particle design by encapsulation

Mots clés

pharmaceutical materials - solid state - preformulation - amorphous - crystal engineering - nanocrystals - encapsulation

Méthodes pédagogiques

courses, conferences, oral exercises, written work.
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